|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Rsf-1 expression in tumor cells in effusions was analyzed for possible association with clinicopathologic parameters and survival.
|
16844205 |
2006 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The above findings suggest that increased Rsf-1 expression and thus excessive RSF activity, which occurs in tumors harboring Rsf-1 amplification, can induce chromosomal instability likely through DDR.
|
20923775 |
2010 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, serum HBXAP DNA levels were not associated with patient age, gender, smoking status, histological type, or tumor size (p > 0.05).
|
23456648 |
2013 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Rsf-1 overexpression was demonstrated in 101 cases (34.2%), and was significantly associated with advanced primary tumour (p<0.001), nodal metastasis (p=0.004), higher histological grades (p=0.001) and frequent mitoses (p<0.001).
|
22685262 |
2012 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
However, there was no correlation between Rsf-1 expression and patient age, peritoneal tumor dissemination, or overall survival.
|
21131837 |
2011 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Positive RSF1 expression was associated with advanced tumour stage, high Gleason grade, lymph node metastasis (<i>p</i> < .0001 each), early biochemical recurrence (<i>p</i> < .0003) and more frequent in the ERG positive than in the ERG negative subset (88% versus 71%; <i>p</i> < .0001).
|
31687881 |
2020 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Rsf-1 overexpression was observed in 25% of high-grade ovarian serous carcinomas and in only rare cases (<7%) of low-grade ovarian serous, ovarian endometrioid, and invasive breast carcinomas but not in any ovarian serous borderline tumors, ovarian clear cell carcinomas, ovarian mucinous carcinomas, intraductal carcinomas of the breast, and normal ovaries and breast tissues.
|
16938522 |
2006 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
The results demonstrated that a high expression level of RSF1 in RCC is associated with advanced tumor stages and a poor prognosis.
|
29467902 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
There was a significant association between Rsf-1 overexpression and tumor stage (p = 0.0322), AFP (p = 0.0184), and tumor relapse (p = 0.0112).
|
24798976 |
2014 |
|
Malignant neoplasm of ovary
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we further demonstrated that RSF1 expression inversely correlated with paclitaxel response in patients with ovarian cancer and the mouse xenograft model.
|
24566868 |
2014 |
|
Carcinoma, Ovarian Epithelial
|
0.070 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we further demonstrated that RSF1 expression inversely correlated with paclitaxel response in patients with ovarian cancer and the mouse xenograft model.
|
24566868 |
2014 |
|
Malignant Neoplasms
|
0.060 |
AlteredExpression
|
group |
BEFREE |
In this study, we performed immunohistochemical analysis on 89 CCCs to assess their expression of Rsf-1 (HBXAP), a chromatin-remodeling gene frequently amplified and overexpressed in several types of human cancer.
|
21131837 |
2011 |
|
Malignant Neoplasms
|
0.060 |
AlteredExpression
|
group |
BEFREE |
<b>Purpose:</b> Aberrant expression and dysfunction of RSF1 has been reported in diverse human malignancies.
|
28261335 |
2017 |
|
ovarian neoplasm
|
0.060 |
AlteredExpression
|
disease |
BEFREE |
In the present study, we further demonstrated that RSF1 expression inversely correlated with paclitaxel response in patients with ovarian cancer and the mouse xenograft model.
|
24566868 |
2014 |
|
Tumor Progression
|
0.050 |
AlteredExpression
|
phenotype |
BEFREE |
The current study by the authors suggests gene amplification-independent mechanisms driving Rsf-1 overexpression during UCUB tumour progression.
|
22685262 |
2012 |
|
Carcinogenesis
|
0.040 |
AlteredExpression
|
phenotype |
BEFREE |
Recently, some studies have indicated that Rsf-1/HBXAP plays a role in chromatin remodeling and transcriptional regulation that may contribute to tumorigenesis in ovarian cancer.
|
20226169 |
2010 |
|
Secondary malignant neoplasm of lymph node
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
Positive RSF1 expression was associated with advanced tumour stage, high Gleason grade, lymph node metastasis (<i>p</i> < .0001 each), early biochemical recurrence (<i>p</i> < .0003) and more frequent in the ERG positive than in the ERG negative subset (88% versus 71%; <i>p</i> < .0001).
|
31687881 |
2020 |
|
Secondary malignant neoplasm of lymph node
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
We found that serum HBXAP DNA levels in lung cancer patients were higher compared to healthy controls (u = 219.0, p = 0.001) and were closely associated with TNM stage and lymph node metastasis (p = 0.015 and p = 0.016, respectively).
|
23456648 |
2013 |
|
Secondary malignant neoplasm of lymph node
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
In conclusion, a higher expression level of Rsf-1 is associated with advanced clinical stage and lymph node metastasis in CCC.
|
21131837 |
2011 |
|
Secondary malignant neoplasm of lymph node
|
0.040 |
AlteredExpression
|
disease |
BEFREE |
There was a significant association between Rsf-1 overexpression and TNM stage (p = 0.0205), lymph node metastasis (p = 0.0025), and poor differentiation (p = 0.0235).
|
22528946 |
2012 |
|
Primary malignant neoplasm
|
0.040 |
AlteredExpression
|
group |
BEFREE |
In this study, we performed immunohistochemical analysis on 89 CCCs to assess their expression of Rsf-1 (HBXAP), a chromatin-remodeling gene frequently amplified and overexpressed in several types of human cancer.
|
21131837 |
2011 |
|
Non-Small Cell Lung Carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
Overexpression of Rsf-1 correlates with poor survival and promotes invasion in non-small cell lung cancer.
|
28289901 |
2017 |
|
Non-Small Cell Lung Carcinoma
|
0.030 |
AlteredExpression
|
disease |
BEFREE |
In conclusion, Rsf-1 is overexpressed in NSCLC and contributes to malignant cell growth by cyclin D1 and ERK modulation, which makes Rsf-1 a candidate therapeutic target in lung cancer.
|
22387541 |
2012 |
|
Neoplasm Metastasis
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
Rsf-1 overexpression was demonstrated in 101 cases (34.2%), and was significantly associated with advanced primary tumour (p<0.001), nodal metastasis (p=0.004), higher histological grades (p=0.001) and frequent mitoses (p<0.001).
|
22685262 |
2012 |
|
Neoplasm Metastasis
|
0.030 |
AlteredExpression
|
phenotype |
BEFREE |
Rsf-1 expression level was significantly lower in primary tumors and solid metastases (P<0.001 for extent, intensity and score).
|
16844205 |
2006 |